Prospective Multi-Center Cohort Study of Atrial Fibrillation Combined with Atrial Functional Mitral Regurgitation
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
To evaluate the improvement of mitral regurgitation after catheter ablation of atrial fibrillation or regular drug therapy in atrial fibrillation patients combined with atrial functional mitral regurgitation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Patients aged 18 to 80 years old;
• Patients diagnosed with symptomatic paroxysmal atrial fibrillation (AF history \< 5 years)
• Moderate to severe MR and normal LV ejection fraction (≥50%), LVEDD\<55 mm, and normal LV wall systolic function
• Able to understand the purpose of the trial, participate in the trial voluntarily with informed consent form signed by the subject him/herself or his or her legal representative, and willing to complete follow-up visits as required under the protocol
Locations
Other Locations
China
Second Affiliated Hospital of Zhejiang University, School of Medicine
RECRUITING
Hangzhou
Contact Information
Primary
Xianbao Liu, Dorctor
liuxb@zju.edu.cn
086-571-87784705
Time Frame
Start Date: 2024-09-27
Estimated Completion Date: 2026-09-30
Participants
Target number of participants: 500
Treatments
Catheter ablation cohort
Patients who receive pulsed field ablation procedure
Drug treatment cohort
Patients who receive regular drug therapy
Related Therapeutic Areas
Sponsors
Leads: Second Affiliated Hospital, School of Medicine, Zhejiang University